A Multicenter Study of Valganciclovir Prophylaxis up to Day 120 in CMV-Seropositive Lung Transplant Recipients
نویسندگان
چکیده
منابع مشابه
Oral Valganciclovir as a Preemptive Treatment for Cytomegalovirus (CMV) Infection in CMV-Seropositive Liver Transplant Recipients
OBJECTIVES Cytomegalovirus (CMV) infections in liver transplant recipients are common and result in significant morbidity and mortality. Intravenous ganciclovir or oral valganciclovir are the standard treatment for CMV infection. The present study investigates the efficacy of oral valganciclovir in CMV infection as a preemptive treatment after liver transplantation. METHODS Between 2012 and 2...
متن کاملLower incidence of CMV infection and acute rejections with valganciclovir prophylaxis in lung transplant recipients
BACKGROUND Cytomegalovirus (CMV) is the most common opportunistic infection following lung transplantation. CMV replication in the lung allograft is described as accelerating the development of bronchiolitis obliterans syndrome (BOS). Finding a strategy to prevent CMV infection is an important issue. METHODS We performed a retrospective, single-centre study of 114 lung transplant recipients (...
متن کاملCMV Infection in CMV-Seropositive Kidney Transplant Recipients
Cytomegalovirus (CMV) infection is a major cause of morbidity in kidney transplant recipients. CMV seropositivity is common in the general population, with a reported prevalence ranging from 30 to 97% (Paya, 2001; Preiksaitis et al., 2005). After primary infection, CMV establishes life-long latency. During the past 2 decades, major advances in the management of CMV infection of transplant patie...
متن کاملProspective follow-up of primary CMV infections after 6 months of valganciclovir prophylaxis in renal transplant recipients.
BACKGROUND The occurrence and clinical course of late primary CMV infections developing after valganciclovir prophylaxis in high-risk renal transplant recipients are poorly described. METHODS Helsinki University Hospital district kidney allograft recipients between January 2004 and March 2007 (N = 175) were prospectively investigated. Patients with D+/R- CMV serostatus and 1-year follow-up we...
متن کاملCytomegalovirus (CMV) immune monitoring with ELISPOT and QuantiFERON-CMV assay in seropositive kidney transplant recipients
Although cytomegalovirus (CMV) specific cell-mediated immunity (CMI) has been suggested as a predictive marker for CMV infection, proper CMI monitoring strategy in CMV-seropositive recipients and optimal method are not defined. The aim of this study was to evaluate two interferon gamma release assays during early post-transplant period as a predictor of the development of CMV infection in CMV-s...
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ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2009
ISSN: 1600-6135,1600-6143
DOI: 10.1111/j.1600-6143.2009.02574.x